Nogo-A inhibits the migration and invasion of human malignant glioma U87MG cells.

@article{Jin2016NogoAIT,
  title={Nogo-A inhibits the migration and invasion of human malignant glioma U87MG cells.},
  author={Shu-Guang Jin and Hyang-Hwa Ryu and Song-Yuan Li and Chun-Hao Li and Sa-Hoe Lim and Woo-Youl Jang and Shin Chul Jung},
  journal={Oncology reports},
  year={2016},
  volume={35 6},
  pages={3395-402}
}
Nogo or reticulon-4 (RTN4), also known as neurite outgrowth inhibitor, is a member of the reticulon family of genes. Nogo-A, one of the three isoforms, is enriched in the central nervous system (CNS). The extracellular domain of Nogo-A, Nogo-66, has neurite growth inhibitory activity that is specific for neurons and is mediated by the Nogo receptor. However, most of its functions are not known yet. We investigated whether Nogo-A modulates the migration and invasion of a glioblastoma cell line… CONTINUE READING

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