Noggin is required for correct guidance of dorsal root ganglion axons.

@article{Dionne2002NogginIR,
  title={Noggin is required for correct guidance of dorsal root ganglion axons.},
  author={Marc S Dionne and Lisa J. Brunet and Peter M Eimon and Richard M Harland},
  journal={Developmental biology},
  year={2002},
  volume={251 2},
  pages={283-93}
}
Members of the bone morphogenetic protein family of secreted protein signals have been implicated as axon guidance cues for specific neurons in Caenorhabditis elegans and in mammals. We have examined axonal pathfinding in mice lacking the secreted bone morphogenetic protein antagonist Noggin. We have found defects in projection of several groups of neurons, including the initial ascending projections from the dorsal root ganglia, motor axons innervating the distal forelimb, and cranial nerve… CONTINUE READING

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