Nodular Cutaneous Amyloidosis at the Temple


A 52-year-old woman presented with a large partially yellow and erythematous tumor on her right temple. She reported that it had grown over the last 4 years. Regional lymph nodes were impalpable. A punch biopsy showed eosinophilic material in the dermis and subcutis. Immunohistochemistry showed positive staining for kappa and lambda light chains. Electron microscopy showed the typical amyloid fibrils (7-10 nm in diameter). There was no evidence of systemic amyloidosis, paraproteinemia or underlying plasmacytoma. The tumor was completely removed via curettage. At follow-up, the patient presented in good health with no signs of relapse.

DOI: 10.1159/000447234

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@inproceedings{Schucht2016NodularCA, title={Nodular Cutaneous Amyloidosis at the Temple}, author={Kathrin Schucht and Josef Schroeder and Heiko I Siegmund and Claudia Grafe and Stephan Schreml}, booktitle={Case reports in dermatology}, year={2016} }