Node-based learning of multiple Gaussian graphical models

  title={Node-based learning of multiple Gaussian graphical models},
  author={Karthik Mohan and Palma London and Maryam Fazel and Daniela M. Witten and Su-In Lee},
  journal={Journal of machine learning research : JMLR},
  volume={15 1},
We consider the problem of estimating high-dimensional Gaussian graphical models corresponding to a single set of variables under several distinct conditions. This problem is motivated by the task of recovering transcriptional regulatory networks on the basis of gene expression data containing heterogeneous samples, such as different disease states, multiple species, or different developmental stages. We assume that most aspects of the conditional dependence networks are shared, but that there… CONTINUE READING
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