Nodal signalling determines biradial asymmetry in Hydra

@article{Watanabe2014NodalSD,
  title={Nodal signalling determines biradial asymmetry in Hydra},
  author={Hiroshi Watanabe and Heiko A. Schmidt and Anne Kuhn and Stefanie K. H{\"o}ger and Yiğit Kocag{\"o}z and Nico Laumann-Lipp and Suat {\"O}zbek and Thomas W. Holstein},
  journal={Nature},
  year={2014},
  volume={515},
  pages={112-115}
}
In bilaterians, three orthogonal body axes define the animal form, with distinct anterior–posterior, dorsal–ventral and left–right asymmetries. The key signalling factors are Wnt family proteins for the anterior–posterior axis, Bmp family proteins for the dorsal–ventral axis and Nodal for the left–right axis. Cnidarians, the sister group to bilaterians, are characterized by one oral–aboral body axis, which exhibits a distinct biradiality of unknown molecular nature. Here we analysed the… Expand
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TLDR
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Left-right asymmetry specification in amphioxus: review and prospects.
  • Vladimír Soukup
  • Biology, Medicine
  • The International journal of developmental biology
  • 2017
TLDR
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TLDR
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TLDR
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On the evolution of bilaterality
TLDR
This Hypothesis compares the molecular control of body axes in radially and bilaterally symmetric cnidarians and bilaterians, identifies the minimal set of traits common for Bilateria, and evaluates whether bilaterality arose once or more than once during evolution. Expand
Interplay between Lefty and Nodal signaling is essential for the organizer and axial formation in amphioxus embryos.
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