Nodal signaling is involved in left-right asymmetry in snails

  title={Nodal signaling is involved in left-right asymmetry in snails},
  author={Cristina Grande and Nipam H. Patel},
Many animals display specific internal or external features with left–right asymmetry. In vertebrates, the molecular pathway that leads to this asymmetry uses the signalling molecule Nodal, a member of the transforming growth factor-β superfamily, which is expressed in the left lateral plate mesoderm, and loss of nodal function produces a randomization of the left–right asymmetry of visceral organs. Orthologues of nodal have also been described in other deuterostomes, including ascidians and… CONTINUE READING
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the expression of Ph-twist and Ph-mef 2 in Parhyale hawaiensis

  • A. L. Price, Patel, N. H. Investigating divergent mechanisms of mesoderm arthropods
  • J. Exp. Zoolog. B Mol. Dev. Evol. 310, 24–40
  • 2008

a comprehensive review

  • Levin, M. Left–right asymmetry in embryonic development
  • Mech. Dev. 122, 3–25
  • 2005

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