Nodal signaling is involved in left-right asymmetry in snails

@inproceedings{Grande2009NodalSI,
  title={Nodal signaling is involved in left-right asymmetry in snails},
  author={Cristina Grande and Nipam H. Patel},
  booktitle={Nature},
  year={2009}
}
Many animals display specific internal or external features with left–right asymmetry. In vertebrates, the molecular pathway that leads to this asymmetry uses the signalling molecule Nodal, a member of the transforming growth factor-β superfamily, which is expressed in the left lateral plate mesoderm, and loss of nodal function produces a randomization of the left–right asymmetry of visceral organs. Orthologues of nodal have also been described in other deuterostomes, including ascidians and… CONTINUE READING
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