Nocturnal recovery of gastric acid secretion with twice-daily dosing of proton pump inhibitors

@article{Peghini1998NocturnalRO,
  title={Nocturnal recovery of gastric acid secretion with twice-daily dosing of proton pump inhibitors},
  author={Paolo L. Peghini and Philip O. Katz and Nicole A Bracy and D. Castell},
  journal={American Journal of Gastroenterology},
  year={1998},
  volume={93},
  pages={763-767}
}
Objective:It is our experience that many patients treated with proton pump inhibitors (PPI) b.i.d. recover acid secretion during the night. Our aim was to assess the efficacy of omeprazole and lansoprazole b.i.d. on nocturnal gastric acidity.Methods:Three groups were studied with intragastric pH monitoring. Group 1 consisted of 17 patients with gastroesophageal reflux disease (GERD) taking omeprazole 20 mg b.i.d. Group 2 was 16 male volunteers taking omeprazole 20 mg b.i.d. and Group 3… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 75 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 26 references

24-hour intragastric acidity and FIG. 3. Mean (6 SE) percentage of time with intragastric pH

  • T Lind, C Cederberg, JP Idström
  • PEGHINI et al. AJG – Vol. 93,
  • 1998
1 Excerpt

Quantitative evaluation of the role of ‘acid-burden’ in production of feline esophagitis

  • KG Pursnani, MA Mohiuddin, KR Geisinger
  • Gastroenterology 1996;110:A235
  • 1996
1 Excerpt

Similar Papers

Loading similar papers…