Nocturnal plasma melatonin levels in patients suffering from chronic primary insomnia.

@article{Hajak1995NocturnalPM,
  title={Nocturnal plasma melatonin levels in patients suffering from chronic primary insomnia.},
  author={Goeran Hajak and Andrea Rodenbeck and Juergen Staedt and Borwin Bandelow and Gerald Huether and Eckart Ruether},
  journal={Journal of pineal research},
  year={1995},
  volume={19 3},
  pages={116-22}
}
Polysomnographic sleep patterns and melatonin secretion were investigated in 10 patients (age: 41.3 +/- 9.5 years) who suffered from chronic primary insomnia and complained predominantly about difficulties in maintaining sleep and in five healthy controls (age 27.2 +/- 0.7 years). Nocturnal plasma melatonin concentrations were obtained hourly, measured by direct radioimmunoassay and statistically compared between insomniacs and controls with age as a covariate. Plasma melatonin levels in the… CONTINUE READING

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