Nocturnal non-invasive ventilation in COPD patients with prolonged hypercapnia after ventilatory support for acute respiratory failure: a randomised, controlled, parallel-group study.

@article{Struik2014NocturnalNV,
  title={Nocturnal non-invasive ventilation in COPD patients with prolonged hypercapnia after ventilatory support for acute respiratory failure: a randomised, controlled, parallel-group study.},
  author={Fransien M Struik and Roy T M Sprooten and H. A. M. Kerstjens and Gerrie Bladder and Marianne Zijnen and Jerryll Asin and Nicolle A M Cobben and Judith M Vonk and P. J. Wijkstra},
  journal={Thorax},
  year={2014},
  volume={69 9},
  pages={826-34}
}
INTRODUCTION The effectiveness of non-invasive positive pressure ventilation (NIV) in COPD patients with prolonged hypercapnia after ventilatory support for acute respiratory failure (ARF) remains unclear. We investigated if nocturnal NIV in these patients prolongs the time to readmission for respiratory causes or death (primary endpoint) in the following 12 months. METHODS 201 COPD patients admitted to hospital with ARF and prolonged hypercapnia >48 h after termination of ventilatory support… CONTINUE READING
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