Nocturnal melatonin secretion in thyroid disease and in obesity.

  title={Nocturnal melatonin secretion in thyroid disease and in obesity.},
  author={Sven R{\"o}jdmark and Andreas Berg and Shirley Roessner and Lennart Wetterberg},
  journal={Clinical endocrinology},
  volume={35 1},
OBJECTIVE The purpose was to investigate whether the function of the pinealocytes is changed in patients with disturbed metabolic rate or in subjects with marked obesity. DESIGN Venous blood was sampled every second hour between 1800 and 0800 h, and urine collected between 2200 and 0700 h. PATIENTS Eight patients with thyrotoxicosis, six with primary hypothyroidism, eight with maturity-onset obesity, and 12 healthy controls were included in the study. MEASUREMENTS Peak serum melatonin… CONTINUE READING

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