Nocturnal continuous positive airway pressure decreases daytime sympathetic traffic in obstructive sleep apnea.

@article{Narkiewicz1999NocturnalCP,
  title={Nocturnal continuous positive airway pressure decreases daytime sympathetic traffic in obstructive sleep apnea.},
  author={Krzysztof Narkiewicz and Masahiko Kato and Bradley G. Phillips and C A Pesek and D. Davison and V. K. Somers},
  journal={Circulation},
  year={1999},
  volume={100 23},
  pages={2332-5}
}
BACKGROUND Patients with obstructive sleep apnea (OSA) have high levels of muscle sympathetic nerve activity (MSNA). We tested the hypothesis that long-term continuous positive airway pressure (CPAP) treatment will decrease MSNA in OSA patients. METHODS AND RESULTS We measured blood pressure, heart rate, and MSNA in 11 normotensive, otherwise healthy patients with OSA who were treated with CPAP. The measurements were obtained at baseline and after 1 month, 6 months, and 1 year of CPAP… CONTINUE READING

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