Nociceptive regulation of GABAB receptor gene expression in rat spinal cord

@article{McCarson1999NociceptiveRO,
  title={Nociceptive regulation of GABAB receptor gene expression in rat spinal cord},
  author={Kenneth E. McCarson and Salvatore J. Enna},
  journal={Neuropharmacology},
  year={1999},
  volume={38},
  pages={1767-1773}
}
Activation of γ-aminobutyric acid (GABA) neurotransmission evokes antinociceptive responses in laboratory animals. The recent cloning of GABAB receptor gene products makes it possible to examine the regulation of this receptor system as it relates to the mediation of pain-related sensory information. Inasmuch as acute and chronic pain alter the expression of a number of nociception-related receptors, and because such changes are important components in the regulation of pain, the present study… CONTINUE READING

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