Nociceptive brain activation in patients with neuropathic pain related to Parkinson's disease.

@article{BrefelCourbon2013NociceptiveBA,
  title={Nociceptive brain activation in patients with neuropathic pain related to Parkinson's disease.},
  author={Christine Brefel-Courbon and Fabienne Ory-Magne and Claire Thalamas and Pierre Payoux and Olivier Rascol},
  journal={Parkinsonism & related disorders},
  year={2013},
  volume={19 5},
  pages={548-52}
}
BACKGROUND Patients suffering from Parkinson's disease (PD) frequently experience painful sensations that may be due to central modification of nociception in PD. We compared pain thresholds and cerebral activity in nociceptive areas using Positron Emission Tomography (PET) during nociceptive stimulation before (OFF condition) and after (ON condition) levodopa challenge between nine PD patients with and nine PD patients without neuropathic pain. METHODS Pain thresholds were determined using a… CONTINUE READING
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