Nociceptive behavior in animal models for peripheral neuropathy: spinal and supraspinal mechanisms.

@article{Saad2008NociceptiveBI,
  title={Nociceptive behavior in animal models for peripheral neuropathy: spinal and supraspinal mechanisms.},
  author={Nayef E. Saad{\'e} and Suhayl J Jabbur},
  journal={Progress in neurobiology},
  year={2008},
  volume={86 1},
  pages={22-47}
}
Since the initial description by Wall [Wall, P.D., 1967. The laminar organization of dorsal horn and effects of descending impulses. J. Neurophysiol. 188, 403-423] of tonic descending inhibitory control of dorsal horn neurons, several studies have aimed to characterize the role of various brain centers in the control of nociceptive input to the spinal cord. The role of brainstem centers in pain inhibition has been well documented over the past four decades. Lesion to peripheral nerves results… CONTINUE READING