Nocebo in clinical trials for depression: A meta-analysis

@article{Mitsikostas2014NoceboIC,
  title={Nocebo in clinical trials for depression: A meta-analysis},
  author={D. Mitsikostas and L. Mantonakis and N. Chalarakis},
  journal={Psychiatry Research},
  year={2014},
  volume={215},
  pages={82-86}
}
  • D. Mitsikostas, L. Mantonakis, N. Chalarakis
  • Published 2014
  • Medicine
  • Psychiatry Research
  • Nocebo refers to adverse events (AEs) related to negative expectations that medical treatment will likely harm instead of heal and can be assessed in placebo-controlled randomized clinical trials (RCTs). We sought to examine the AEs following placebo administration in RCTs for depression (D). After a systematic Medline search for RCTs in depression published in the last decade we assessed percentages of placebo-treated patients reporting at least one AE or discontinuing due to placebo… CONTINUE READING
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