NoFold: RNA structure clustering without folding or alignment.

@article{Middleton2014NoFoldRS,
  title={NoFold: RNA structure clustering without folding or alignment.},
  author={Sarah A Middleton and Junhyong Kim},
  journal={RNA},
  year={2014},
  volume={20 11},
  pages={1671-83}
}
Structures that recur across multiple different transcripts, called structure motifs, often perform a similar function-for example, recruiting a specific RNA-binding protein that then regulates translation, splicing, or subcellular localization. Identifying common motifs between coregulated transcripts may therefore yield significant insight into their binding partners and mechanism of regulation. However, as most methods for clustering structures are based on folding individual sequences or… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 5 times. VIEW TWEETS

References

Publications referenced by this paper.
Showing 1-10 of 44 references

Infernal 1.0: inference of RNA alignments

View 4 Excerpts
Highly Influenced

Fast and reliable prediction of noncoding RNAs.

Proceedings of the National Academy of Sciences of the United States of America • 2005
View 3 Excerpts
Highly Influenced

Input space versus feature space in kernel-based methods

IEEE Trans. Neural Networks • 1999
View 1 Excerpt
Highly Influenced

Rfam 11.0: 10 years of RNA families

Nucleic Acids Research • 2013
View 3 Excerpts

Similar Papers

Loading similar papers…