No support for endoscopic surveillance for gastric cancer in hereditary non-polyposis colorectal cancer.

@article{RenkonenSinisalo2002NoSF,
  title={No support for endoscopic surveillance for gastric cancer in hereditary non-polyposis colorectal cancer.},
  author={Laura Renkonen-Sinisalo and Pentti Ilmari Sipponen and Markku Aarnio and Risto J. K. Julkunen and Lauri A. Aaltonen and Seppo S Sarna and Heikki J{\"a}rvinen and J. P. Mecklin},
  journal={Scandinavian journal of gastroenterology},
  year={2002},
  volume={37 5},
  pages={
          574-7
        }
}
BACKGROUND The DNA mismatch repair gene mutations underlying hereditary non-polyposis colorectal cancer syndrome (HNPCC) also predispose, besides colorectal and endometrial cancer, to gastric cancer. usually of the intestinal type. The carcinogenetic pathway behind the elevated gastric cancer risk is largely unknown. METHODS The aim of this study was to determine whether there are any premalignant lesions to search for in gastric surveillance in HNPCC by comparing gastric histopathology… CONTINUE READING
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