No support for association between the dopamine transporter (DAT1) gene and ADHD.

@article{Langley2005NoSF,
  title={No support for association between the dopamine transporter (DAT1) gene and ADHD.},
  author={Kate Langley and Dragana Turic and Timothy R Peirce and Sophie Mills and Marianne Bernadette van den Bree and Michael J Owen and Mick C O'Donovan and Anita Thapar},
  journal={American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics},
  year={2005},
  volume={139B 1},
  pages={7-10}
}
Several groups have reported an association between the 10-repeat allele of a dopamine transporter (DAT1) 3'UTR VNTR variant and ADHD but the finding has not been universally observed. An association between DAT1 genotype and stimulant medication response has also been reported although again there are conflicting data. We tested the DAT1 3'VNTR and three SNPs in the putative promoter region of DAT1 for association with ADHD in 263 parent-proband trios. Analyses of genotypes, alleles, and… CONTINUE READING