No relationship between the digit ratios (2D:4D) and salivary testosterone change: Study on men under an acute exercise

  title={No relationship between the digit ratios (2D:4D) and salivary testosterone change: Study on men under an acute exercise},
  author={Marta Kowal and Piotr Sorokowski and Agnieszka Żelaźniewicz and Judyta Nowak and Sylwester Orzechowski and Grzegorz Żurek and Alina Żurek and Anna Juszkiewicz and Lidia Wojtycka and Wiktoria Sieniu{\'c} and Malgorzata Poniatowska and Karolina Tarnowska and Kaja Kowalska and Katarzyna Drabik and Patrycja Łukaszek and Krzysztof Krawczyk and Tadeusz Stefaniak and Natalia Danek},
  journal={Scientific Reports},
The digit ratio (2D:4D) is said to be a potential marker of exposure to prenatal sex steroids. Some studies suggest that the 2D:4D is also linked with the testosterone response to challenging situations due to organizational effect of prenatal hormonal milieu on adult endocrine functioning. However, up to date, there were only four studies (conducted on small samples) that examined the 2D:4D and the testosterone response to a challenging situation (i.e. physical exertion or aggressive context… 

Associations between second to fourth digit ratio, cortisol, vitamin D, and body composition among Polish children

Neither vitamin D, 2D:4D digit ratio nor the cortisol level was associated with the body components or proportions, which might indicate an effect of prenatal programming on the concentrations of steroid hormones in later life.

Thyroid diseases and second to fourth digit ratio in Polish adults

Only females who had thyroid diseases tend to have higher 2D:4D digit ratio, for left hand, forLeft hand, and the association between thyroid diseases occurrence and prenatal steroid hormone exposition is noticed.

Oxytocin receptor gene polymorphism (rs53576) and digit ratio associates with aggression: comparison in seven ethnic groups

The data suggest that both oxytocin ( OXTR gene polymorphism) and fetal testosterone (2D:4D) may significantly affect emotional (anger) and cognitive (hostility) aggression in humans, given the leveling the role of culture.

Effects of Dominance and Sprint Interval Exercise on Testosterone and Cortisol Levels in Strength-, Endurance-, and Non-Training Men

Simple Summary Exercise is a powerful stimulus to the endocrine system, modifying plasma concentrations of many hormones, including testosterone and cortisol, which are often used to describe fatigue

Exploring Finger Digit Ratios (2D:4D) in Surgeons, Professional Rugby Players, and Political Journalists to Form a Directional Hypothesis: Could Finger Length Predict Attention and Focus?

It is argued 2D:4D is likely predictive of testosterone sensitivity and associated ability to focus attention; a skill important to high achievement in various contexts.

Variation among human populations in endometriosis and PCOS A test of the inverse comorbidity model

  • B. Crespi
  • Biology
    Evolution, medicine, and public health
  • 2021
Data from the literature on the prevalence of endometriosis and PCOS, levels of serum testosterone in women during pregnancy and digit ratios as indicators of prenatal testosterone provided convergent, preliminary support for the inverse comorbidity model.

Modest Exercise-Induced Increases in Testosterone Concentration Are Not Associated with Mating Strategy Change in Healthy Young Men

Research has demonstrated that increases in testosterone (T) concentration can affect the expression of behaviours and preferences that are typical of high mating effort. However, little research has



Right–left digit ratio (2D:4D) predicts free testosterone levels associated with a physical challenge

It is suggested that low right–left 2D:4D is a predictive marker of free testosterone responsiveness when trained men are physically challenged, and that this association is programmed by the action of prenatal testosterone.

Digit Ratio (2D:4D): A Biomarker for Prenatal Sex Steroids and Adult Sex Steroids in Challenge Situations

It is hypothesized that 2D:4D correlates with organizing effects on the endocrine system that moderate activating effects in adulthood, and is particularly evident in “challenging” conditions such as aggressive and sexual encounters, in which individuals show increased levels of T.

Second to fourth digit ratio (2D:4D) and testosterone in men.

Adult levels of testosterone may be related to aspects of 2D:4D in samples which contain men with compromised testicular function, but not in men from normative samples.