No prognostic impact of flow-cytometric measured DNA ploidy and S-phase fraction in cancer of the uterine cervix: a prospective study of 465 patients.

@article{Kristensen1995NoPI,
  title={No prognostic impact of flow-cytometric measured DNA ploidy and S-phase fraction in cancer of the uterine cervix: a prospective study of 465 patients.},
  author={Gunnar Balle Kristensen and Janne Kaern and V. M. Abeler and Bj\orn M Hagmar and Claes G{\"o}ran Trop{\'e} and Erik Olai Pettersen},
  journal={Gynecologic oncology},
  year={1995},
  volume={57 1},
  pages={79-85}
}
In a prospective study of 465 patients with invasive carcinoma of the uterine cervix, the prognostic impact of flow cytometric parameters (ploidy level and fraction of S-phase cells) and clinical variables was evaluated. Median follow-up time was 57 (32-80) months. A total of 230 patients died of cervical cancer during follow-up. Ploidy level had no prognostic significance, neither when analyzed as diploid against nondiploid nor when utilizing different cutoff levels for DNA index (1.3, 1.5… CONTINUE READING
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