No pharmacokinetic effect of retaining the infusion site up to four days during continuous subcutaneous insulin infusion therapy.

Abstract

This study was designed to investigate whether the indwelling time of the needle during continuous subcutaneous insulin infusion (CSII) could contribute to one of the main problems with subcutaneous insulin administration, that is the day-to-day intra-patient variation in absorption. The effect on insulin kinetics after a bolus dose was investigated at… (More)

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