No pain relief from morphine? Individual variation in sensitivity to morphine and the need to switch to an alternative opioid in cancer patients.

@article{Riley2006NoPR,
  title={No pain relief from morphine? Individual variation in sensitivity to morphine and the need to switch to an alternative opioid in cancer patients.},
  author={Julia H. Riley and Joy R. Ross and Dag Rutter and Athol U Wells and K. Goller and Roland M du Bois and Ken Ian Welsh},
  journal={Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer},
  year={2006},
  volume={14 1},
  pages={56-64}
}
GOALS OF WORK The aims of this study were (1) to prospectively evaluate the clinical benefits of switching from morphine to an alternative opioid, using oxycodone as first-line alternative opioid, in patients with cancer, (2) to evaluate the consistency of the clinical decision for the need to switch by comparing two hospital sites, and (3) to evaluate whether there were objective predictors that would help identify morphine non-responders who require switching to an alternative opioid and from… CONTINUE READING
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