No mutation was found in the alpha-subunit of the mitochondrial tri-functional protein in one patient with severe acute fatty liver of pregnancy and her relatives.

@article{Kong2007NoMW,
  title={No mutation was found in the alpha-subunit of the mitochondrial tri-functional protein in one patient with severe acute fatty liver of pregnancy and her relatives.},
  author={Xiao-fei Kong and Xin-Xin Zhang and Ying-yan Yu and Qing Shi and D La and Chuan-De Zhu-Ge and Lin Deng and Qi-ming Gong and Bai-yong Shen and Cheng-Hong Peng and Hongwei Li},
  journal={Journal of gastroenterology and hepatology},
  year={2007},
  volume={22 12},
  pages={2107-11}
}
BACKGROUND AND AIM Acute fatty liver of pregnancy (AFLP) is a serious hepatic disorder and a devastating late gestational complication associated with substantial maternal and neonatal morbidity and mortality. Several studies have demonstrated a strong association between AFLP in the mother and fetal deficiency of the enzyme long-chain L-3 hydroxyacyl-CoA dehydrogenase (LCHAD). LCHAD resides in the alpha-subunit of the mitochondrial tri-functional protein and catalyzes the third step in the… CONTINUE READING