No intrinsic deficiencies in CD8+ T cell-mediated antitumor immunity with aging.

@article{Norian2004NoID,
  title={No intrinsic deficiencies in CD8+ T cell-mediated antitumor immunity with aging.},
  author={Lyse A Norian and Paul E. Allen},
  journal={Journal of immunology},
  year={2004},
  volume={173 2},
  pages={835-44}
}
Aging is associated with a decline in immune function, particularly within the T cell compartment. Because CD8(+) T cells are critical mediators of protective immunity against cancer, which arises more frequently with advancing age, it is important to understand how aging affects T cell-based antitumor responses. We used our DUC18 T cell/CMS5 tumor model… CONTINUE READING