No improvement in cardiovascular risk factors in overweight and obese subjects after supplementation with vitamin D3 for 1 year

@article{Jorde2010NoII,
  title={No improvement in cardiovascular risk factors in overweight and obese subjects after supplementation with vitamin D3 for 1 year},
  author={R. Jorde and M. Sneve and P. Torjesen and Y. Figenschau},
  journal={Journal of Internal Medicine},
  year={2010},
  volume={267}
}
Abstract.  Jorde R, Sneve M, Torjesen P, Figenschau Y (University of Tromsø, Tromsø; Medical Clinic University Hospital of North Norway, Tromsø; University Hospital of North Norway, Tromsø; Aker University Hospital, Oslo; University Hospital of North Norway, Tromsø; and University of Tromsø, Tromsø; Norway). No improvement in cardiovascular risk factors in overweight and obese subjects after supplementation with vitamin D3 for 1 year. J Intern Med 2010; 267:462–472. 
Vitamin D3 supplementation does not modify cardiovascular risk profile of adults with inadequate vitamin D status
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Daily supplementation of 20 µg vitamin D3 during winter is unlikely to change cardiovascular risk profile, although serum 25-hydroxyvitamin D3 increased from 38 ±-14 to 73 ± 16 nmol/L at week 12, although blood pressure and systemic cardiovascular risk markers remained unchanged. Expand
Ameliorative impact of vitamin D on hypertension
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Meta-analysis of cohort studies showed that vitamin D deficiency, predicts enhanced risk of all-cause mortality, cardiovasculardisease, and hypertension and several mechanisms proposed thatitamin D decreases blood pressure. Expand
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An optimal vitamin D status may influence cardiovascular health by changing the lipid profile in a favorable direction and decreasing the incidence of the metabolic syndrome. Expand
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Background: It is unclear whether and at what dose vitamin D supplementation affects insulin resistance (IR). Objective: We sought to investigate whether vitamin D at doses higher than currentlyExpand
Editorial The relationship between vitamin D and obesity
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Vitamin D deficiency is associated with the presence of a cardiometabolic risk profile in the obese and future trials may establish a role for Vitamin D supplementation in individuals at increased CV risk. Expand
The relationship between vitamin D and obesity
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Concentrations of 25-hydroxyvitamin D (25(OH)D) (25D) are considered as the best indicator of total body vitamin D stores and an association between reduced circulating 25D concentrations and obesity is well known. Expand
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Investigating whether vitamin D at doses higher than currently recommended decreases indexes of IR in an ambulatory population of overweight elderly subjects found that HOMA-IR was predicted by the baseline HOMa index and BMI but not by vitamin D dose, baseline serum 25( OH)D, or change in 25(OH)D. Expand
Effects of Vitamin D on Blood Pressure and Cardiovascular Risk Factors: A Randomized Controlled Trial
TLDR
Vitamin D supplementation in hypertensive patients with low 25-hydroxyvitamin D has no significant effect on BP and several cardiovascular risk factors, but it was associated with a significant increase in triglycerides. Expand
A prospective study of serum 25-hydroxyvitamin D levels, blood pressure, and incident hypertension in postmenopausal women.
TLDR
In postmenopausal women in this study, serum levels of 25(OH)D were not related to changes in blood pressure, and evidence for an association with lower risk of incident hypertension was weak. Expand
Effects of vitamin D2 supplementation on insulin sensitivity and metabolic parameters in metabolic syndrome patients
TLDR
Vitamin D2 20,000 IU per week and 40,000IU per week givn for 8 weeks, were able to increase serum 25(OH)D concentrations significantly more than placebo group, however, HOMA-IR was not significantly different in the three groups. Expand
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The failure of vitamin D supplementation to change blood pressure or serum cholesterol suggests that the winter increase in these factors is not caused by decreased vitamin D levels. Expand
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