No exit: targeting the budding process to inhibit filovirus replication.

Abstract

The filoviruses, Ebola and Marburg, cause severe hemorrhagic fever in humans and nonhuman primates, with high mortality rates. Although the filovirus replication pathway is now understood in considerable detail, no antiviral drugs have yet been developed that directly inhibit steps in the replication cycle. One potential target is the filovirus VP40 matrix… (More)
DOI: 10.1016/j.antiviral.2008.12.003

Cite this paper

@article{Harty2009NoET, title={No exit: targeting the budding process to inhibit filovirus replication.}, author={Ronald N Harty}, journal={Antiviral research}, year={2009}, volume={81 3}, pages={189-97} }