No evidence of involvement of Chlamydia pneumoniae in severe cerebrovascular atherosclerosis by means of quantitative real-time polymerase chain reaction.

@article{Apfalter2004NoEO,
  title={No evidence of involvement of Chlamydia pneumoniae in severe cerebrovascular atherosclerosis by means of quantitative real-time polymerase chain reaction.},
  author={Petra Apfalter and Wolfgang Barousch and Marion Nehr and Birgit Willinger and Manfred Rotter and Alexander M. Hirschl},
  journal={Stroke},
  year={2004},
  volume={35 9},
  pages={2024-8}
}
BACKGROUND AND PURPOSE All studies reporting high numbers of Chlamydia pneumoniae DNA positives in stroke patients published to date have used polymerase chain reaction (PCR) techniques highly prone to generate false-positive results. The aim of this study was to analyze the prevalence of C. pneumoniae DNA in plaques of the carotid artery as well as in peripheral blood by means of a new, closed, real-time PCR system. METHODS Carotid endarterectomy specimens and preoperative peripheral blood… CONTINUE READING

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