No evidence of hSNF5/INI1 point mutations in choroid plexus papilloma.

@article{Mueller2004NoEO,
  title={No evidence of hSNF5/INI1 point mutations in choroid plexus papilloma.},
  author={Wolf C. Mueller and J-H David Eum and Ulrich Lass and W. Paulus and Chitra Sarkar and Wolfgang Bruck and Andreas von Deimling},
  journal={Neuropathology and applied neurobiology},
  year={2004},
  volume={30 3},
  pages={304-7}
}
Choroid plexus carcinomas (CPC) have been shown to carry mutations in the hSNF5/INI1 gene on chromosomal arm 22q11.2. A recent study on choroid plexus papillomas (CPP) and CPC revealed frequent losses of chromosomal portions on the long arm of chromosome 22 (-22q). The region harbouring hSNF5/INI1 was affected in 47% of the CPP and 73% of the CPC, respectively. -22q occurred more frequently in adult than in infantile CPP suggesting different pathogenetic pathways for these tumours. These… CONTINUE READING

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