No evidence of a trial effect in newly diagnosed pediatric acute lymphoblastic leukemia.

@article{Koschmann2010NoEO,
  title={No evidence of a trial effect in newly diagnosed pediatric acute lymphoblastic leukemia.},
  author={Carl Koschmann and Blythe Thomson and Douglas S Hawkins},
  journal={Archives of pediatrics & adolescent medicine},
  year={2010},
  volume={164 3},
  pages={214-7}
}
OBJECTIVE To determine whether clinical trial enrollment by itself is associated with improved outcome. DESIGN Retrospective cohort study. SETTING Seattle Children's Hospital from 1997 to 2005. PARTICIPANTS Data were drawn from 322 patients with newly diagnosed acute lymphoblastic leukemia. Main Exposure Enrollment in a Children's Oncology Group or Children's Cancer Group clinical trial. MAIN OUTCOME MEASURES (1) Demographic variables associated with trial participation. (2) Event-free… CONTINUE READING

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