No evidence for systemic oxidant stress in Parkinson's or Alzheimer's disease.

@article{Ahlskog1995NoEF,
  title={No evidence for systemic oxidant stress in Parkinson's or Alzheimer's disease.},
  author={J. Eric Ahlskog and Ryan J. Uitti and Phillip A. Low and Gertrude M. Tyce and Kim K Nickander and Ronald C. Petersen and Emre Kokmen},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  year={1995},
  volume={10 5},
  pages={566-73}
}
Oxidant stress secondary to dopamine metabolism has been proposed as a pathogenic factor in the development of Parkinson's disease. Biochemical abnormalities extending beyond the central nervous system have been identified in patients with this condition. Previous investigators have found abnormally elevated concentrations of the lipid peroxidation product, malondialdehyde, in the plasma and serum of patients with Parkinson's disease. We attempted to replicate these findings but controlled for… CONTINUE READING

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