No evidence for significant association between GABA receptor genes in chromosome 15q11-q13 and autism in a Japanese population

@article{Tochigi2007NoEF,
  title={No evidence for significant association between GABA receptor genes in chromosome 15q11-q13 and autism in a Japanese population},
  author={Mamoru Tochigi and Chieko Kato and Shinko Koishi and Yuki Kawakubo and Kenji Yamamoto and Hideo Matsumoto and Ohiko Hashimoto and Soo-Yung Kim and Keiichiro Watanabe and Yukiko Kano and Eiji Nanba and Nobumasa Kato and Tsukasa Sasaki},
  journal={Journal of Human Genetics},
  year={2007},
  volume={52},
  pages={985-989}
}
AbstractThe γ-aminobutyric acid (GABA) receptor genes GABRB3, GABRA5, and GABRG3 located on chromosome 15q11-q13 have been major candidates for susceptibility genes for autism, a neurodevelopmental disorder with a complex genetic etiology. In this study, we first investigated the association between the GABA receptor genes and autism in a Japanese population by analyzing 11 single nucleotide polymorphisms (SNPs). Intron 3 of GABRB3 was densely mapped because the previous studies observed the… CONTINUE READING