No evidence for generalized increased postoperative responsiveness to pain: a combined behavioral and serial functional magnetic resonance imaging study.

Abstract

BACKGROUND Although it is generally accepted that increased pain responsiveness and central sensitization develop after major tissue injury, this claim has not been tested using brain imaging methods in a clinical pain setting. We tested this hypothesis using a postoperative pain model, in conjunction with serial functional magnetic resonance imaging (fMRI… (More)
DOI: 10.1213/ane.0b013e3181ac1866

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@article{Kupers2009NoEF, title={No evidence for generalized increased postoperative responsiveness to pain: a combined behavioral and serial functional magnetic resonance imaging study.}, author={Ron Kupers and Fabien C. Schneider and Rune Christensen and Arne Naert and Henrik Husted and Olaf B. Paulson and Henrik Kehlet}, journal={Anesthesia and analgesia}, year={2009}, volume={109 2}, pages={600-6} }