No evidence for association between the KCNQ3 gene and susceptibility to idiopathic generalized epilepsy.

@article{Haug2000NoEF,
  title={No evidence for association between the KCNQ3 gene and susceptibility to idiopathic generalized epilepsy.},
  author={Karsten Haug and Kerstin Hallmann and Steve Horvath and Thomas K. Sander and Christian Kubisch and B. Ramarishna Rau and Joern S. Dullinger and Stefan Beyenburg and Christian Erich Elger and P. Propping and Armin Heils},
  journal={Epilepsy research},
  year={2000},
  volume={42 1},
  pages={57-62}
}
Idiopathic generalized epilepsy (IGE) comprises a heterogeneous group of disorders, in which a high genetic predisposition and a complex mode of inheritance have been suggested. Recent identification of ion channel gene mutations in Mendelian epileptic disorders suggests genetically driven neuronal hyperexcitability as one important factor in epileptogenesis. Mutations in two neuronal voltage-gated potassium channel genes (KCNQ2 and KCNQ3) have already been shown to cause epilepsy (BFNC), and… CONTINUE READING