No evidence for allelic association of serotonin 2A receptor and transporter gene polymorphisms with depression in Alzheimer disease.

@article{Micheli2006NoEF,
  title={No evidence for allelic association of serotonin 2A receptor and transporter gene polymorphisms with depression in Alzheimer disease.},
  author={Dario Micheli and Cristian Bonvicini and A. Rocchi and R Ceravolo and M Mancuso and Gloria Tognoni and Massimo Gennarelli and Gabriele Siciliano and L. Murri},
  journal={Journal of Alzheimer's disease : JAD},
  year={2006},
  volume={10 4},
  pages={371-8}
}
Patients with Alzheimer disease (AD) often exhibit psychiatric symptoms associated with cognitive impairment. The serotoninergic system may be involved in the development of depressive symptoms in AD patients, as suggested by the evidence that antidepressant drugs having the serotonin transporter as their target are effectively used to treat depressive AD patients. The aim of this study was to investigate the role of serotonin in depression, searching for association of two serotoninergic… CONTINUE READING
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