No effect of bicarbonate-induced alkalosis on urea synthesis in normal man.

Abstract

The effect of metabolic alkalosis was studied in 10 healthy volunteers. In each person urea synthesis was determined in two periods of 2 h as urinary excretion corrected for accumulation in body water and for intestinal hydrolysis. Infusion of bicarbonate (115 mmol/h) increased pH of the venous blood by 0.10 units. In four subjects fasting urea synthesis… (More)

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@article{Bjerrum1990NoEO, title={No effect of bicarbonate-induced alkalosis on urea synthesis in normal man.}, author={Katje Bjerrum and Hendrik Vilstrup and Thomas Peter Almdal and L Ostergaard Kristensen}, journal={Scandinavian journal of clinical and laboratory investigation}, year={1990}, volume={50 2}, pages={137-41} }