No effect of an elevated miR-30b level in mouse milk on its level in pup tissues

@inproceedings{Laubier2015NoEO,
  title={No effect of an elevated miR-30b level in mouse milk on its level in pup tissues},
  author={Johann Laubier and Johan Castille and Sandrine Le Guillou and Fabienne le Provost},
  booktitle={RNA biology},
  year={2015}
}
Recent reports have shown that ingested microRNAs may be transferred to blood, accumulate in tissues and exert canonical regulation on endogenous transcripts. In spite of several attempts to replicate these findings, they have not been confirmed and several questions remain. By using a transgenic mouse model presenting a high level of miR-30b in milk, the horizontal delivery of this microRNA via oral ingestion was studied in pups. Our findings demonstrated that, although very high levels of miR… CONTINUE READING
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