No direct mitogenic effect of sex hormones on antlerogenic cells detected in vitro.

@article{Li2001NoDM,
  title={No direct mitogenic effect of sex hormones on antlerogenic cells detected in vitro.},
  author={Chunyi Li and Wenqiang Wang and Teas Manley and James M. Suttie},
  journal={General and comparative endocrinology},
  year={2001},
  volume={124 1},
  pages={75-81}
}
Deer pedicles, antecedents of antlers, develop from a specialized periosteum (antlerogenic periosteum) which overlies the lateral crest of the deer frontal bone. The initiation of pedicle growth is triggered by androgen hormones. Thus far, it is not known whether pedicle initiation is caused by direct stimulation of androgen hormones on the antlerogenic periosteum or whether some intermediate mechanisms are necessary. The present study took an in vitro approach to investigate whether sex… CONTINUE READING

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