No difference in graft-versus-host disease, relapse, and survival comparing peripheral stem cells to bone marrow using unrelated donors.

@article{Remberger2001NoDI,
  title={No difference in graft-versus-host disease, relapse, and survival comparing peripheral stem cells to bone marrow using unrelated donors.},
  author={Mats Remberger and Olle Ringd{\'e}n and I W Blau and Helmut Ottinger and Bernhard Kremens and M G Kiehl and Johan Aschan and Dietrich W. Beelen and Nadezda Basara and Gunilla Kumlien and A. Fauser and Volker Runde},
  journal={Blood},
  year={2001},
  volume={98 6},
  pages={1739-45}
}
The clinical results in 107 patients receiving a peripheral blood stem cell (PBSC) graft mobilized by granulocyte colony-stimulating factor (G-CSF) from HLA-A, -B, and -DR-compatible unrelated donors were compared to 107 matched controls receiving unrelated bone marrow (BM) transplants. Engraftment was achieved in 94% of the patients in both groups. The PBSC graft contained significantly more nucleated cells, CD34(+), CD3(+), and CD56(+) cells (P <.001), and resulted in a significantly shorter… CONTINUE READING
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