No detectable remote lesions following massive intrastriatal injections of ibotenic acid

@article{Guldin1981NoDR,
  title={No detectable remote lesions following massive intrastriatal injections of ibotenic acid},
  author={Wolfgang O. Guldin and Hans Joachim Markowitsch},
  journal={Brain Research},
  year={1981},
  volume={225},
  pages={446-451}
}
Behavioral and anatomical consequences of particularly large intrastriatal injections of ibotenic acid are described. Only in the rat with the largest injection, which encompassed almost the entire frontal lobe, were enduring aphagia and adipsia observed; epileptic attacks were, however, not detectable in this or in any other of the rats. In spite of the massiveness of the lesion, neither remote lesions nor damage to passing fibers was observed. It is therefore suggested to substitute kainic… CONTINUE READING
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