No contribution of multipotent mesenchymal stromal cells to liver regeneration in a rat model of prolonged hepatic injury.

@article{Popp2007NoCO,
  title={No contribution of multipotent mesenchymal stromal cells to liver regeneration in a rat model of prolonged hepatic injury.},
  author={Felix Cristoph Popp and Przemyslaw Slowik and Elke Eggenhofer and Phillip Renner and Sven Arke Lang and Oliver Stoeltzing and Edward Kenneth Geissler and Pompiliu Piso and Hans J. Schlitt and Marc Hendrik Dahlke},
  journal={Stem cells},
  year={2007},
  volume={25 3},
  pages={639-45}
}
Multipotent mesenchymal stromal (MS) cells from adult bone marrow are a cell population that can be expanded to large numbers in culture. MS cells might be differentiated toward hepatocytes in vitro and thus are promising candidates for therapeutic applications in vivo. The efficacy of bone marrow-derived MS cells versus hepatocytes to contribute to liver regeneration was compared in a rat model of prolonged toxic hepatic injury. Liver damage was induced by injection of carbon tetrachloride… CONTINUE READING
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