No benefit of endoscopic sphincterotomy before biliary placement of self-expandable metal stents for unresectable pancreatic cancer.

@article{Hayashi2015NoBO,
  title={No benefit of endoscopic sphincterotomy before biliary placement of self-expandable metal stents for unresectable pancreatic cancer.},
  author={Tsuyoshi Hayashi and Hiroshi Kawakami and Manabu Osanai and Hirotoshi Ishiwatari and Hirohito Naruse and Hiroyuki Hisai and Nobuyuki Yanagawa and Hiroyuki Kaneto and Kazuya Koizumi and Tamaki Sakurai and Tomoko Sonoda},
  journal={Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association},
  year={2015},
  volume={13 6},
  pages={
          1151-8.e2
        }
}
BACKGROUND & AIMS Endoscopic sphincterotomy (ES) is performed routinely before self-expandable metallic stents (SEMS) are placed in malignant distal biliary strictures to prevent postprocedural pancreatitis. However, it is not clear whether ES actually prevents pancreatitis or affects other adverse events (AEs). We conducted a noninferiority trial to examine the necessity of ES before SEMS placement. METHODS Two hundred patients with distal biliary strictures caused by unresectable pancreatic… CONTINUE READING
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