No association of MDM2 SNP309 with risk of glioblastoma and prognosis

@article{Hallani2007NoAO,
  title={No association of MDM2 SNP309 with risk of glioblastoma and prognosis},
  author={Soufiane El Hallani and Yannick Marie and Ahmed Idbaih and Mathieu P Rodero and Blandine Boisselier and Florence Laigle-Donadey and François Ducray and Jean-Yves Delattre and Marc Sanson},
  journal={Journal of Neuro-Oncology},
  year={2007},
  volume={85},
  pages={241-244}
}
The MDM2 SNP309 variant has been shown to increase MDM2 expression and to be associated with tumor formation. In glioblastomas, the P53/MDM2 pathway is of crucial importance and MDM2 amplification is related to poor prognosis. However, we show here that MDM2 SNP309 is not associated with glioblastoma risk, and is not a prognostic factor. 

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