No association found between 158 Val/Met polymorphism of the COMT gene and schizophrenia with minor physical anomalies.

@article{Joo2005NoAF,
  title={No association found between 158 Val/Met polymorphism of the COMT gene and schizophrenia with minor physical anomalies.},
  author={Eun-jeong Joo and Seong-Hoon Jeong and Yong Min Ahn and Kyu Bak Lee and Se Chang Yoon and Eui-Joong Kim and S Kim and Soo-Churl Cho and Yong Sik Kim},
  journal={Psychiatry research},
  year={2005},
  volume={136 2-3},
  pages={83-91}
}
The catechol-O-methyl transferase (COMT) gene has been a promising candidate in genetic research on schizophrenia because of its function in dopamine metabolism and its location on chromosome 22q11.2, which may be implicated in both schizophrenia and velocardiofacial syndrome (VCFS). To explore the possible genetic contribution of COMT to the development of schizophrenia, we focused on the subgroup of patients with schizophrenia characterized by minor physical anomalies as a phenotype and the… CONTINUE READING

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