No association between the sigma receptor type 1 gene and schizophrenia: results of analysis and meta-analysis of case-control studies

Abstract

BACKGROUND Several lines of evidence have supported possible roles of the sigma receptors in the etiology of schizophrenia and mechanisms of antipsychotic efficacy. An association study provided genetic evidence that the sigma receptor type 1 gene (SIGMAR1) was a possible susceptibility factor for schizophrenia, however, it was not replicated by a… (More)

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