No association between multiple sclerosis and the Notch3 gene responsible for cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

@article{Broadley2001NoAB,
  title={No association between multiple sclerosis and the Notch3 gene responsible for cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).},
  author={Simon A. Broadley and Stephen J Sawcer and Simon Jeremy Chataway and Francesca Coraddu and Alasdair John Coles and Julia Gray and Robert Roxburgh and David G. Clayton and D. Alastair S. Compston},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={2001},
  volume={71 1},
  pages={97-9}
}
The clinical and radiological overlap between multiple sclerosis and cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL; MIM 125310) raises the possibility of diagnostic confusion and suggests that pleiotropic effects of the Notch3 gene might include influencing susceptibility to multiple sclerosis. To… CONTINUE READING