No association between (AAT)n repeats in the cannabinoid receptor gene (CNR1) and heroin abuse in a Chinese population

@article{Li2000NoAB,
  title={No association between (AAT)n repeats in the cannabinoid receptor gene (CNR1) and heroin abuse in a Chinese population},
  author={Tao Li and Xiaohua Liu and Z H Zhu and Jing Hua Zhao and Xun Hu and David M. Ball and Pak C. Sham and David A. Collier},
  journal={Molecular Psychiatry},
  year={2000},
  volume={5},
  pages={128-130}
}
MP c c 16 03 00 09 14 37 R 15 01 $$$$499 Chronic CRF hypersecretion results in down regulation of pituitary CRF receptors and a blunted ACTH response to exogenous CRF. This has been reported in patients with post-traumatic stress disorder and in patients with major depressive disorders. Research with animal models indicates that adverse events in early life can have a permanent impact on the CRF control system. In rats, early maternal deprivation can result in long term HPA-CRF activation. Liu… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

The genetics of substance dependence.

Annual review of genomics and human genetics • 2012
View 1 Excerpt

Polymorphisms in CRHR1 and the Serotonin Transporter Loci: Gene × Gene × Environment Interactions on Depressive Symptoms

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics • 2010

Similar Papers

Loading similar papers…