No adverse hemodynamic interaction between sildenafil and red wine

@article{Leslie2004NoAH,
  title={No adverse hemodynamic interaction between sildenafil and red wine},
  author={S. Leslie and G. Atkins and J. Oliver and D. Webb},
  journal={Clinical Pharmacology \& Therapeutics},
  year={2004},
  volume={76}
}
Our objective was to investigate the hemodynamic interaction between sildenafil and red wine. Sildenafil citrate (Viagra), a phosphodiesterase type 5 inhibitor, is an effective treatment for male erectile dysfunction that potentiates nitric oxide–mediated vasodilation. Alcohol is a commonly used recreational substance with complex vascular effects, which may, in part, be mediated by nitric oxide. Thus there is potential for an adverse hemodynamic interaction. 
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References

SHOWING 1-10 OF 29 REFERENCES
Sildenafil citrate and blood-pressure-lowering drugs: results of drug interaction studies with an organic nitrate and a calcium antagonist.
Sildenafil citrate potentiates the hypotensive effects of nitric oxide donor drugs in male patients with stable angina.
Overall cardiovascular profile of sildenafil citrate.
Effects of sildenafil citrate on human hemodynamics.
Sildenafil (Viagra) is used as a recreational drug in England
The effect of sildenafil on human vascular function, platelet activation, and myocardial ischemia.
ORAL SILDENAFIL IN THE TREATMENT OF ERECTILE DYSFUNCTION
...
1
2
3
...