No Effect of NGAL/lipocalin-2 on Aggressiveness of Cancer in the MMTV-PyMT/FVB/N Mouse Model for Breast Cancer

@inproceedings{Cramer2012NoEO,
  title={No Effect of NGAL/lipocalin-2 on Aggressiveness of Cancer in the MMTV-PyMT/FVB/N Mouse Model for Breast Cancer},
  author={Elisabeth Pr{\ae}stekj{\ae}r Cramer and Andreas Glenth\oj and Mattias H{\"a}ger and Anna Juncker-Jensen and Lars Henning Engelholm and Eric Santoni-Rugiu and Leif R\oge Lund and Ole Didrik Laerum and Jack Bernard Cowland and Niels Borregaard},
  booktitle={PloS one},
  year={2012}
}
NGAL/lipocalin-2 is a siderophore-binding protein that is highly expressed in several cancers. It is suggested to confer a proliferative advantage to cancer cells. Its expression has been correlated with aggressiveness of breast cancer as determined both in patients and in mouse breast cancer models. This was recently confirmed in two mouse models of… CONTINUE READING