No Difference in Myosin Kinetics and Spatial Distribution of the Lever Arm in the Left and Right Ventricles of Human Hearts

@inproceedings{Duggal2017NoDI,
  title={No Difference in Myosin Kinetics and Spatial Distribution of the Lever Arm in the Left and Right Ventricles of Human Hearts},
  author={Divya Duggal and Susana Alexandra Lavayen Requena and Janhavi Nagwekar and Sangram Raut and Ryan Rich and H. K. Das and Vipul A. Patel and Ignazy. Gryczynski and Rafal Fudala and Zygmunt Karol Gryczynski and Cheavar Anthony Blair and Kenneth S. Campbell and Julian Borejdo},
  booktitle={Front. Physiol.},
  year={2017}
}
The systemic circulation offers larger resistance to the blood flow than the pulmonary system. Consequently, the left ventricle (LV) must pump blood with more force than the right ventricle (RV). The question arises whether the stronger pumping action of the LV is due to a more efficient action of left ventricular myosin, or whether it is due to the morphological differences between ventricles. Such a question cannot be answered by studying the entire ventricles or myocytes because any observed… CONTINUE READING
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