No Association between Donor Telomere Length and Outcomes after Allogeneic Unrelated Hematopoietic Cell Transplant in Patients with Acute Leukemia

@inproceedings{Gadalla2017NoAB,
  title={No Association between Donor Telomere Length and Outcomes after Allogeneic Unrelated Hematopoietic Cell Transplant in Patients with Acute Leukemia},
  author={Shahinaz M Gadalla and Tao Wang and David Loftus and Lyssa Friedman and Casey L Dagnall and Michael D. Haagenson and Stephen R. Spellman and Ljubomir Buturovi{\'c} and Marsha Blauwkamp and Jason Shelton and Katharina Fleischhauer and Katharine C Hsu and Michael R. Verneris and Damjan Krstajic and Belynda Hicks and Kristine Jones and Stephanie J Lee and Sharon A Savage},
  booktitle={Bone Marrow Transplantation},
  year={2017}
}
Recent studies suggest improved survival in patients with severe aplastic anemia receiving hematopoietic cell transplant (HCT) from unrelated donors with longer telomeres. Here, we tested whether this effect is generalizable to patients with acute leukemia. From the Center for International Blood and Marrow Transplant Research (CIBMTR®) database, we identified 1097 patients who received 8/8 HLA-matched unrelated HCT for acute myeloid leukemia (AML) or acute lymphocytic leukemia (ALL) between… CONTINUE READING